Trulicity cost in 2026, and the Medicare price coming in 2028
Trulicity costs $389 a month for four weekly pens at any dose when paid in cash, against a list price of $987.
Trulicity, Lilly’s once-weekly dulaglutide pen for type 2 diabetes and cardiovascular risk in diabetes, has a single self-pay price of $389 a month for 0.75, 1.5, 3 and 4.5 mg, published on TrumpRx and filled through LillyDirect. That is 61 % below its $987 list price, and below what pharmacies pay for it, about $975 according to the NADAC survey. On Medicare, Part D covers it: in 2026 your share under the standard benefit reaches the $2,100 cap in July at list price, and in 2027, with a $2,400 cap, a year costs about $2,400. CMS selected Trulicity for the third round of Medicare price negotiation, with a negotiated price taking effect in 2028; that price has not been published yet.
The whole of 2026, by way of paying
- Paying cash (self-pay)$4,668
- Medicare Part D, covered use$2,100
- Medicaid, at a $4.00 copay$48
You would pay, Trulicity 1.5 mg
$389 / month
$4,668 in 2026
Self-pay price published by LillyDirect / TrumpRx, the same through both.
Same dose, other ways to pay (per month)
- List price (wholesale acquisition cost)$987
- Self-pay: LillyDirect or TrumpRx$389
- What pharmacies pay (NADAC)$975
- Medicare Part D, your share (month avg., 2026)$175
TrumpRx and makers read on October 16, 2026 · NADAC file of October 14, 2026. Estimate only, not medical advice. How it is calculated
Prices read by Radif Partners · Editorial policy · Method and data
Four strengths, one price
Like Mounjaro, Trulicity is priced per carton of four single-dose pens, whatever the strength. The label starts adults at 0.75 mg and allows steps of 1.5 mg every four weeks up to 4.5 mg; none of those steps changes a cash bill.
| Strength | Self-pay a month | List price | Pharmacy cost (NADAC) |
|---|---|---|---|
| 0.75 mg | $389 | $987 | $975 |
| 1.5 mg | $389 | $987 | $975 |
| 3 mg | $389 | $987 | $975 |
| 4.5 mg | $389 | $987 | $975 |
Selected for 2028
The Inflation Reduction Act lets Medicare negotiate the price of drugs with high Part D spending that have been on the market for years. Trulicity is on the list of fifteen drugs CMS selected for prices that apply from January 1, 2028, alongside Biktarvy, Xolair and others; the negotiated amounts are not public yet. Until then, Part D plans pay their own contracted price and your share follows the standard rules. The negotiated prices page tracks every selected drug.
Cash or coverage
For an uninsured patient, the self-pay price is a large cut on what a pharmacy would otherwise charge. With employer coverage that includes Trulicity, Lilly’s savings card lets you pay as little as $25, saving at most $150 a month and $1,950 a year until December 31, 2026. Without the card, check your plan’s copay first: if it is above the self-pay price, paying cash may cost less month to month, but those payments do not count toward your deductible or out-of-pocket maximum.